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A comment on A Hidden Origin Story of the CBD Craze. Parent comment

Re:A Hidden Origin Story of the CBD Craze by TheSpiceIsLife on Saturday May 23, 2020 @09:24PM (#23288248)
> read: it won't make you go crazy

What is this supposed to mean?

Is high potency marijuana making people go / act crazy?

If so, I wasn’t aware of that and would like to know more.

[ Parent | on HN ]
Re:A Hidden Origin Story of the CBD Craze by macawfish on Saturday May 23, 2020 @11:51PM (#23288930)
Oh definitely this has been fairly well established for a while now. THC is pro-psychotic/anxiogenic in high enough doses and CBD is anti-psychotic/anxiolytic in high enough doses. The balance is crucial. And yes this has been backed up by studies showing that people smoking weed with higher THC/CBD ratio are more prone to psychotic break, and others showing that CBD can actually alleviate psychotic symptoms. CBD is even used in very large doses (~1 gram!) to treat schizophrenia.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604190/ https://www.sciencedirect.com/science/article/pii/S092099641...

The balance is really important and there are a lot of individual factors.

[ Parent | on HN ]
Re:A Hidden Origin Story of the CBD Craze by TheSpiceIsLife on Sunday May 24, 2020 @01:30AM (#23289366)
Oh, right, I see now. Thanks for explaining that and providing the references.
[ Parent | on HN ]
Re:A Hidden Origin Story of the CBD Craze by dkn775 on Sunday May 24, 2020 @01:12AM (#23289289)
Even if it’s not go crazy in the traditional sense, I know for me I can’t smoke like in college, I get extremely anxious.
[ Parent | on HN ]