I'm not sure if anecdotes are allowed or welcomed, hope this is okay: Around 2003 I learnt about lysine having something to do with preventing HSV-1, so I got some and took some large doses until the bottle was finished. Haven't had a cold sore since, and I was getting them ~yearly before. Sometimes I can feel the tingling and think shiiit, here it comes again finally, but I never really had a proper breakout.

Also, the more I hear about the HSV/Alzheimer's link, the more I freak out about my shitty memory :(