This is a good question. Also important to remember is that for many Linux distributions dynamically linked OpenSSL artifacts are what end up getting used by the vast majority of binaries.

Yeah, I was thinking by all of the binaries. I had forgotten that there's software that bundle it independently of the distro's library. Another comment mentioned docker images, and I've remembered that ruby also bundles it for its own use.

I have no idea what a full list looks like.. but the nginx:1.17.10-alpine docker image contains the following:

    / # nginx -V                              
    nginx version: nginx/1.17.10
    built by gcc 9.2.0 (Alpine 9.2.0)
    built with OpenSSL 1.1.1d  10 Sep 2019

Mine has a "running with..." part after that.

    built with OpenSSL 1.1.1d  10 Sep 2019 (running with OpenSSL 1.1.1g  21 Apr 2020)

If it doesn't print the "running with" line, it's running with the same version it was built with:

https://hg.nginx.org/nginx/file/stable-1.18/src/core/nginx.c...

Any embedded system that uses a recent version of buildroot and includes openssl. Starting with at least version 2019.02.9

MySQL