Study: No evidence of efficacy of hydroxychloroquine in hospitalized patients

Re:Study: No evidence of efficacy of hydroxychloroquine in h... by shadowgovt on Wednesday April 15, 2020 @01:44PM (#22880711)

Question: are the induced arrhythmias permanent or do they discontinue when HCQ therapy discontinues?

I'm curious as to the permanency of the damage.

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Re:Study: No evidence of efficacy of hydroxychloroquine in h... by epmaybe on Wednesday April 15, 2020 @01:48PM (#22880749)

the qt prolongation of heart rhythm goes away once discontinued.

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Re:Study: No evidence of efficacy of hydroxychloroquine in h... by jamesblonde on Wednesday April 15, 2020 @05:50PM (#22883500)

Qt prolongation does not mean you have arrhythmias. You don't get tachycardia or atrial flutter or necessarily sympthoms. Clinically if it means there is a risk if the QT interval gets to long that you will have a fatal arrhythmia - torsades de pointes. So you need to know how bad the Qt prolongation is. In the paper 2 patients had serious side effects - one with QT prolongation over 500ms and the second with a first-degree atrioventricular block. Another maybe had a left bundle branch (not great, but not fatal). They resolved by stopping HCQ treatment.

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Re:Study: No evidence of efficacy of hydroxychloroquine in h... by epmaybe on Wednesday April 15, 2020 @07:07PM (#22884215)

I didn't claim that the QT prolongation implied arrhythmia.

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