Re:SARS-CoV-2 titers in wastewater are higher than expected ...
by indecisive_user on Friday April 10, 2020 @10:20AM
(#22833271)
Correct me if I'm wrong, but this used PCR testing to determine the number of _currently_ infected people. It says nothing about the number of people that _were_ infected, but fought off the virus and are now potentially immune.
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Re:SARS-CoV-2 titers in wastewater are higher than expected ...
by Retric on Friday April 10, 2020 @10:46AM
(#22833536)
Simple exposure is not enough to become immune. You need a significant infection which triggers a strong immune system response to build long term immunity. Thus in the initial stages of an outbreak you can basically ignore people that became infected weeks ago, had a significant infection, and are now immune due to the exponential growth curve.
It’s only after the rate of infection stayed the same or falls for a month+ that you need to adjust for such people.
Re:SARS-CoV-2 titers in wastewater are higher than expected ...
by indecisive_user on Friday April 10, 2020 @11:23AM
(#22833955)
>You need a significant infection which triggers a strong immune system response to build long term immunity.
I don't think this is true. I get the flu shot every year and have never had a strong immune response to it, yet I'm still immune to the major flu strains each year.
Point being, it's possible for your body to create long term immunity to a virus without suffering from a severe infection.
Re:SARS-CoV-2 titers in wastewater are higher than expected ...
by Retric on Friday April 10, 2020 @11:27AM
(#22833990)
I am specifically referring to COVID-19 where we don’t have a vaccine. Vaccines fake a significant infection to get that same strong immune response. This is also why some vaccines require multiple doses over a short period.
Re:SARS-CoV-2 titers in wastewater are higher than expected ...
by mannykannot on Friday April 10, 2020 @11:03AM
(#22833716)
If we did know the true current infection rate (which this report does not give, as there are too many unresolved assumptions), then could we not, with some reasonable assumptions about the rate of spread and the duration of an infection, estimate the number who have recovered from it?
Re:SARS-CoV-2 titers in wastewater are higher than expected ...
by coldcode on Friday April 10, 2020 @10:26AM
(#22833316)
I think that requires an antibody test