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Re:Fatal toxicity of chloroquine or hydroxychloroquine with ... by nwienert on Sunday April 05, 2020 @03:43PM (#22788012)
Can you cite it not working for covid-19 in vivo? From what I've found there are early stage trials showing success, plus a few larger anecdotal populations showing bigger success, but nothing that scientifically definitively concludes either way.
Re:Fatal toxicity of chloroquine or hydroxychloroquine with ... by ComputerGuru on Sunday April 05, 2020 @03:52PM (#22788089)
Yes, there simply hasn’t been enough time for proper studies to have been made one way or the other [0]. The only “study” showing in vivo efficacy is pretty much a bunch of bunk and has huge issues. It did not report on actual treatment outcomes but only on nasal swab results without a control arm, never mind that covid-19 has been demonstrated to move from upper respiratory down into the lungs in most cases that progress to pneumonia or respiratory distress anyway (so a nasal swab says nothing and can come back negative while the patient is dying of respiratory failure).

[0]: https://www.cebm.net/covid-19/chloroquine-and-hydroxychloroq...

Re:Fatal toxicity of chloroquine or hydroxychloroquine with ... by nwienert on Sunday April 05, 2020 @03:56PM (#22788118)
That means your claim that it “only works in vitro” is false, though. The right claim would be “we don’t know yet”.

Also you do a lot of work to make it sound like a foregone conclusion it doesn’t work (appeals to authority in “anyone paying attention”).

The problem is there is now a lot of anecdotal evidence of it working from good sources (teams of doctors on frontlines from around the world). So really you can’t appeal to anyone paying attention.

Re:Fatal toxicity of chloroquine or hydroxychloroquine with ... by ComputerGuru on Sunday April 05, 2020 @04:16PM (#22788318)
Yes, so far as we know.