It was several years ago, so I don't remember the details, but I have heard echos of the sentiment in the recent criticism of alzheimers research. I.e. that amyloid plaques may actually be the equivalent of a cellular AC that's been misidentified as the reason the room is hot.

https://www.nature.com/articles/d41586-018-05719-4

>“The current approach is based on the idea that amyloid-β is bad,” says Perry. “My idea is the opposite.” He suggests that amyloid-β and tau accumulation is actually a protective response to age-related metabolic pressures in the cell.