Not OP but I can say that on Windows it may require a lot of fiddling. Hardware drivers appear to be a big factor.

Another concern is the many overlays that accompany game launchers and drivers, including: Nvidia, Steam, GOG, etc. These add latency and sometimes private notifications.

The fiddling step was what I hoped to minimize. Did you have better luck with Linux or MacOS?

Interface is similar across the platforms; I had to do a few test streams on macOS before I could find settings that didn't cause streaming hiccups or problems with other software. I also had to make sure the OBS app interface was on a monitor separate from the one I was streaming; otherwise sometimes it would have some weird stuttering issues.

No matter what, you'll probably need to spend a little time tweaking things to get it all working like you want. But the 'scenes' and preferences are pretty good about letting you lock things down once you do find something you like.

Linux. Kubuntu 18.4 to be precise.