Note also that it is possible the virus has evolved to spread more easily, which in the context of a lot of screening and social distancing of symptomatic people would mean more asymptomatic spreading.
Medical Mask also meant even though the case broke out in a city with very high population density, the spread is far lower ( again comparatively speaking ).
https://grapevine.is/news/2020/03/15/first-results-of-genera...
From the article about Covid-19 serologic test development:
> The serologic tests, which are different from the ones used to diagnose active infection, would allow researchers to test the blood of people who were not confirmed cases of Covid-19 in communities where the virus spread. They would be designed to look for signs that people have mounted an immune response after being exposed to the virus.
https://www.statnews.com/2020/03/11/cdc-developing-serologic...
Not that I know of. On the most recent "This Week in Virology" podcast, they mentioned that China has recently said they won't be doing serologic testing, which lead them to think that China has reason to believe the disease is far more widespread than their official numbers show. This may be in line with the idea that most infections are asymptomatic.
> "The current PCR test only tells you whether a person has the virus at this moment," Dr Meru Sheel, an epidemiologist and research fellow at the Australian National University said.
> "What it doesn't tell you is that a person may have had the infection, has recovered and is immune or not immune."
> Dr Sheel said a serological test would help understand at population level how many people have been exposed to the disease, have recovered and if there are populations that are not immune to the virus.
https://www.abc.net.au/news/2020-03-17/coronavirus-experts-c...
So long as every asymptomatic person got it from someone with symptoms, they necessarily a source of contagion. Is the conclusion based on modeling, i.e. that the rate of spread is only consistent with the asymptomatic people also trasmitting the virus?
Lots of asymptomatic infected doesn't (automatically) mean lots of transmission from asymptomatic people to uninfected people.
The Professor of Clinical Immunology of the University of Florence, Sergio Romagnani
> Asymptomatic infection has been reported, but the majority of the relatively rare cases who are asymptomatic on the date of identification/report went on to develop disease. The proportion of truly asymptomatic infections is unclear but appears to be relatively rare and does not appear to be a major driver of transmission.
https://www.who.int/docs/default-source/coronaviruse/who-chi...
> Clinical and epidemiological data from the Chinese CDC and regarding 72,314 case records (confirmed, suspected, diagnosed, and asymptomatic cases) were shared in the Journal of the American Medical Association (JAMA) (February 24, 2020), providing an important illustration of the epidemiologic curve of the Chinese outbreak. There were 62% confirmed cases, including 1% of cases that were asymptomatic, but were laboratory-positive (viral nucleic acid test).
https://www.ncbi.nlm.nih.gov/books/NBK554776/
Weird discrepancy on the order of 75x. I'd love to trust the experts, but who? I am leaning towards truly asymptomatic spread being rare, since you get infected by SARS-CoV-2, not COVID-19 (COVID-19 is the disease), the level of uncertainty of 25% is higher than for other reports, and the main reported mode of transmission is through symptomatic cough droplets.