Chloroquine has shown apparent efficacy in treatment of Covid-19

Re:Chloroquine has shown apparent efficacy in treatment of C... by ethbro on Monday March 16, 2020 @11:41PM (#22601407)

> allowing time to clear the virus from the body without raising an excessive immune response ("cytokine storm")

Citation requested, that cytokine storms are a common pathology associated with Covid-19.

Because (a) I haven't seen that in the literature, & (b) it's at odds with the published age-banded mortality rates.

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Re:Chloroquine has shown apparent efficacy in treatment of C... by tlb on Monday March 16, 2020 @11:43PM (#22601422)

https://www.thelancet.com/journals/lancet/article/PIIS0140-6...

Not common but very serious.

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Re:Chloroquine has shown apparent efficacy in treatment of C... by IAmEveryone on Tuesday March 17, 2020 @01:09AM (#22601904)

For reasons beyond my understanding, the internet (or maybe just HN) has been in love with cytokines storms for a decade or so. Far more than warranted by the actual significance of the phenomenon relative to others.

It’s like quicksand in 19th century pop culture.

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Re:Chloroquine has shown apparent efficacy in treatment of C... by drewmol on Tuesday March 17, 2020 @01:00AM (#22601846)

"We propose that the immunomodulatory effect of hydroxychloroquine also may be useful in controlling the cytokine storm that occurs late-phase in critically ill SARS-CoV-2 infected patients."

[0]https://academic.oup.com/cid/advance-article/doi/10.1093/cid...

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[dead]

Re:Chloroquine has shown apparent efficacy in treatment of C... by nl on Monday March 16, 2020 @11:59PM (#22601511)

It's settled fact that the covid-19 pneumonia is a result of a "cytochine storm".

This just isn't true. It maybe true for a subset of patients in some circumstances. To quote your first link:

Accumulating evidence suggests that a subgroup of patients with severe COVID-19 might have a cytokine storm syndrome.

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