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Re:Open letter from Italy to the international scientific co... by ComputerGuru on Saturday March 14, 2020 @08:27PM (#22579923)
You can’t fast track things past what they’ve already been fast tracked. Stop second guessing the experts. What is the use of a hurried vaccine tomorrow if next month it turns out to cause birth defects or global infertility or cancer.
Re:Open letter from Italy to the international scientific co... by mrfusion on Saturday March 14, 2020 @08:53PM (#22580109)
I’m sure there’s still a ton of bureaucracy. We need to go back to first principles and really look at what makes a drug safe and how quickly we can find out.

And also take a look at what safeguards we are willing to cut when every day of delay is thousands of deaths.

Re:Open letter from Italy to the international scientific co... by mrfusion on Saturday March 14, 2020 @08:54PM (#22580116)
Birth defects and infertility aren’t issues for most of these patients.
Re:Open letter from Italy to the international scientific co... by ComputerGuru on Monday March 16, 2020 @03:40PM (#22596718)
You don’t vaccinate patients, you treat them. Everyone else gets the vaccine. These are absolutely concerns for the people that would be vaccinated.
Re:Open letter from Italy to the international scientific co... by lbeltrame on Saturday March 14, 2020 @08:36PM (#22579984)
> You can’t fast track things past what they’ve already been fast tracked. Stop second guessing the experts

I'm well aware of how trials work (I happen to work in a scientific institution which does plenty). They may have been fast-tracked elsewhere, but not in my country.

So far there's just compassionate use, which means they're administered only to people who have truly severe sympthoms.

A vaccine can wait, to be honest, it's not as critical as a treatment to lessen the sympthoms. In fact, that's why Gilead is also testing their drug here (not sure when the actual protocols will start, though).

Note that I'm not advocating for "let's scrap all the trials stuff". But trials in phase III have, for obvious reasons, very lengthy time frames. And it's not the first time (I attended a talk a few years ago on the topic) where the system (which works, normally) shows its limits (not only emergencies, but for example orphan drugs).