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Re:Sucralose with carbohydrates may blunt the body’s ability... by vonmoltke on Tuesday March 10, 2020 @01:58PM (#22537796)
> Metformin is a pretty serious drug and that is a high dose.

According to a former endocrinologist of mine, 1000mg daily is the lowest effective dose. 500mg pills are the lowest dose available. What is your source for 1000mg being a "high dose"?

Re:Sucralose with carbohydrates may blunt the body’s ability... by Spooky23 on Wednesday March 11, 2020 @09:40AM (#22545713)
For diabetes or PCOS, sure.

What is the effective dose for general life extension?