It never even occurred to me to do that but trying it now, I don't think it's feasible for my hands. Either my palm mashes CTRL, ALT, and CMD (and sometimes FN and Shift) or I have a super awkward angle to get to the C key. It seems much easier to just drop my pinky down for half a second.

EDIT: After a suggestion from another user, I just remapped my Caps Lock to CTRL. That seems a lot easier to deal with. I'll try that for a bit and see how it goes.