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Re:Ask HN: What's the best resource for learning modern x64 ... by xxs on Sunday February 09, 2020 @03:38AM (#22281074)
Started with 6502 (pretty much the only way to get any reasonable speed/working was Assembly).

Switching to 8086 was so awkward: it had built in div, instruction, the rep prefix but most importantly so many bits - 16. I routinely used ah/al and the like.

Learning Assembly is quite easy on its right own, ability to write optimal code and routinely being compilers is a whole another story. Writing the inner loops (like grep) is what's usually left to on modern processors.

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