Re:FDA approves first US phage therapy trial (2019)
by Fomite on Monday January 27, 2020 @09:19PM
(#22165838)
Phage therapy was researched by Félix d'Hérelle, a french-canadian scientist who was awarded the Leeuwenhoek Medal. Eli Lilly and Company were working on commercializing it in the U.S.
The problem was phage therapy couldn't stand up to a disruptive idea: the large scale production of penicillin in the mid-40's.
Re:FDA approves first US phage therapy trial (2019)
by BurningFrog on Monday January 27, 2020 @10:21PM
(#22166142)
Didn't know that.
But I can see how it seemed that penicillin had solved that problem forever back then.
Re:FDA approves first US phage therapy trial (2019)
by Fomite on Monday January 27, 2020 @10:34PM
(#22166199)
Indeed. While Flemming himself was concerned about resistance, penicillin is:
1) Much broader spectrum than phage preparations 2) Easier to manufacture in large quantities 3) Safer, because you don't need to filter the prep to remove endotoxins
It's basically a silver bullet - if you don't look too far in the future. It was incredibly disruptive.
Now it's much harder for disruptive ideas to make it past the "peer wall".