Ben Goldacre's bad science is a great book on this topic. He's an entertaining speaker too. He describes a solution to that particular problem which is registering a clinical trials beforehand.
https://www.theguardian.com/business/2012/oct/07/ben-goldacr...
Science is incredibly broken in many ways. I think the big underlying culprit is the prevailing ideology that every human activity is best organized as a competition for scarce resources.
Then gradually re-enculture review boards to expect any given author to have a substantial number of results published to said repository, if they're actively performing research.
Can you resolve / flesh this out more? If the desire for funding is a key driver of behavior then it would seem most anything is possible, including conspiracy or related nefarious activites.
Humans, especially those with big ideas and big egos, in pursuit of fortune and fame have been known to bend and break the rules.
It happens in a lot of places. And to be honest it’s what most of the people want and while places like r/nba are more neutral and give respect where it is due, ESPN knows the casual 12yr old knows Lebron James and Steph Curry and they recruit “talent” to only talk about them, not just what is going well for the sport as a whole.
It’s a difficult balance that is really up to the power players and the quality of leadership to get right.
With science though you’d hope far more meritocracy than big names, but sadly I believe this is a human and non-expert efficiency thing (as most people are not really experts). Some people might blame capitalism of the bio firms but they are just the sum of their people who run and fund them too.
We're not good at thinking rationally about things that involve our own benefit. We'll more often than not only think things through to the point where we avoid breaking any existing rules but still go with the lazy choice that benefits us in the short term.
If you're in a modern, first-world country you get to decide which part of the Pareto 80/20 divide you sit on.
The world doesn't need more mediocre people.
Most relevant is that he was against consensus science, which was highlighted in the submission. Even if you are 'wrong' and in the group consensus, all is forgiven. If you are 'right' but not in the group, you are blackballed, and if you are wrong and not in the group consensus, you are crucified.
In academia it is tied to laurels and funding. The clue in the article was defender of the so-called cabal saying if it were true, it was because the NIH Alzheimers funding was too low, i.e. it was a fight for who would get what research grants. Go against the concensus and be blacklisted.
Just one data point, but in my experience in academia that was almost exactly how I found it. The exception that it wasn't a team sport because there's only space for one first author.
My feeling is that the recognition and 'impactfulness' tied to being successful in academia are antagonistic to conducting unbiased research.