> It’s inflammation of the brain, and eating a low inflammation diet (low carb, no sugar, fasting) is the best thing one can do to drastically reduce getting it.

Do you have a source?

If you state something like this with such authority/in a "matter of fact" way (and is something that seems likely to be controversial), you really should have a source.

Here u go: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2769828/

I'm not sure that I would state that it's inflammation as a fact, but exercise most likely will not hurt. Peter Attia, who is fanatical about understanding longevity, has said multiple times that he believes the best thing someone can do for long term brain health is exercise every day.

If it does turn out that inflammation is the cause, then things like fasting will also help.

I thought that it was also strongly associated with gum disease: https://www.alzheimers.net/alzheimers-and-gingivitis-disease...

Yes, which drove suspicion of a bacterial link.

It could be quite complex -- bacteria helping herpes, or herpes helping bacteria into the brain, and the brain responding to one or the other or both with inflammation and plaques. And maybe something else involved, like inadequate or excess dietary intake of something like sugar, or trans fats, or PCBs, or glyphosate.

We need to explore many, many possibilities.

Gum disease is linked to carbohydrates, which aligns with the "type 3 diabetes" hypothesis.

(carbs feed bacterial overgrowth)

Gum disease is also linked to being old, just like Alzheimers disease, heart disease, baldness, wrinkly faces, diabetic disease and lots of other things. Sermon: people are really, really shit at linear regression.

The logic that chronic illness can’t be prevented and is either genetic or inevitable is so problematic.

Like everyone is going to get old and if I think getting old means I will inevitably get gum disease which could cause Alzheimer’s then why bother flossing or caring about preventative oral health?

I think his point was that these symptoms could be correlation, not causation. So you need to work to prevent each of them as you age. (Eg that flossing is good for your oral health, even though it might have no influence on other factors associated with being old)

#1: you're going to die, and while you can stave it off by living a certain way, there's ultimately nothing you can do about it.

#2: gum disease is correlated with age. Alzheimers is also correlated with age. The connection between the two correlations is age. That means there is basically no evidence gum disease causes Alzheimers any more than heart disease or having wrinkles on your forehead causes gum disease.

I agree.

I remember seeing that but I really suspect it's a gross oversimplification and not likely to be very explanatory. Almost like science clickbait. But not saying there isn't some connection....

Not every conclusion suggesting a chronic illness is largely preventable through diet and exercise is “clickbait”