Re:Biopharma has abandoned antibiotic development
by heavyset_go on Monday December 16, 2019 @07:06PM
(#21809038)
Apparently, most antibiotics don't undergo metabolism in animals, and 40-90% of ingested antibiotics in livestock are excreted in urine and feces[1].
Those antibiotics go on to contaminate groundwater, and as you say, contribute significantly to antibiotic resistance[2].
[1] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4220964/
[2] https://en.wikipedia.org/wiki/Antibiotic_use_in_livestock#An...
This is part of the problem. If animals are given the antibiotics, then their waste products contain them, and piles of manure or water runoff/storm drains/wastewater ponds form a giant evolutionary experiment for development of drug resistant organisms.
They're not just a problem while they're in animals, they're a problem if they're used at all.