Working in VR is a cool glimpse of the future. I also sometimes do it with Immersed VR (similar to VR Desktop, but works with Mac). I say glimpse, because I still kind of need to "force" myself to do it.

There are some advantages (like the big screen and more focus), but today the disadvantage will overweigh for most people (friction of putting on the headset and connecting to your computer over WiFi, the weight of the headset, lower resolution, starting to sweat over time and leaving marks on your face, etc.).

However, these are very solvable engineering problms and I'm exteremly optimistic that working in VR will be better than looking at a "small" flat screen sooner than most people realize.