Those who "make" liquidity by publicly quoting ask/bids are rebated fractions of a cent when their orders are filled, and those who "take" liquidity by exercising the Maker's position are charged.
This is separate to the spreads. The book Flash Boys has a very good explanation of the model.
[1] https://www.investopedia.com/articles/active-trading/042414/...
* Number of successful trades = 1
* Number of unsuccessful trades = 999,999
* Profit on successful trade = 1000000
* Loss on each unsuccessful trade = -1
* Net profit: $1
* Net profit/trade: $0.00001
So Virtu profits on 51-52% of its trades. The type of math you are describing does not make any sense. Unless Virtu is significantly different from every other HFT firm, your idea of high asymmetry of profit and losses is not true.