Psilocybin for major depression granted Breakthrough Therapy by FDA

Re:Psilocybin for major depression granted Breakthrough Ther... by Frondo on Tuesday November 26, 2019 @03:23PM (#21642293)

I had an experience of total amnesia on LSD once. After a few minutes (objective, by a wall clock) of time-dilation experience (felt like 8 or 10 hours passing), I wandered upstairs and laid down on the bed. Again, a few minutes of closed-eye visuals that felt like hours passed, and when I opened my eyes, I had absolutely no idea who I was, even down to my name, where I lived, nothing. The only thing I could say was "I exist," without being able to qualify that in any way at all, and by staring at the room around me, "I'm in a room, seems to be in a city." Very, very strange experience. Suddenly, no more visuals, but it took the next few hours for details about myself, my hobbies, my work, etc., to start filtering back in.

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Re:Psilocybin for major depression granted Breakthrough Ther... by mirimir on Tuesday November 26, 2019 @05:07PM (#21643233)

Huh.

Did you take any other drugs?

I've experienced stuff like that at high LSD dosages, but it wasn't unpleasant. In fact, I liked it. It's what I meant by "ego death".

That is, there's no awareness that an "I" exists. There's just stuff happening. Inside, outside, all the same. Just stuff.

And then gradually, there's this internal dialog that starts talking about all the stuff. That is, consciousness, what I'm calling ego aka "I".

With marijuana during LSD peaking, that happens abruptly. With sometimes considerable anxiety.

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Re:Psilocybin for major depression granted Breakthrough Ther... by spurgu on Wednesday November 27, 2019 @09:56PM (#21654269)

I had this on alcohol + an unhealthy dose of psilocybin, apart from the difference where the only thing I could think was "I don't even know what 'exist' means". Scary but luckily I had some close friends that were comforting me throughout the experience.

For the most part though, my small experiments (LSD, mushrooms, DMT) have had a very positive and borderline revolutional effect on my outlook on life. Only time I've had negative experiences have been on mushrooms, both LSD and DMT have always been positive.

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Re:Psilocybin for major depression granted Breakthrough Ther... by eaenki on Tuesday November 26, 2019 @05:13PM (#21643284)

That sounds scary af

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Re:Psilocybin for major depression granted Breakthrough Ther... by perl4ever on Tuesday November 26, 2019 @07:28PM (#21644188)

I've had modern anesthesia for surgery twice in my life, and that seems to operate mostly by temporarily eliminating your ability to form memories. I found that "scary af" even though it certainly worked as expected.

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