And also Python like programs. And probably Node.js like programs. And really anything where you have lots of I/O to do.

I would rather use PyPy in Python's case.

I would not because I still have to deal with the language and tooling, even if the implementation is much faster.

Dealing with the language is exactly why I would rather advise to use PyPy, instead of completely change ecosystem.

Go would not even be on my list for Python developers looking for performance.

There are much better AOT compiled languages with a feature set similar to Python.

Such as? Go is what Python should have been in my mind, although I would love a more expressive type system. But overall it generally replaces Python for me.