When growing up I had to prepare for the possibility that I’d go totally blind one day (thankfully that did not happen). One of the best things that was ever done for me was getting regular touch-typing lessons from a young age.
On screen readers - I’m really excited to see what ML could bring to the table here. I think accessibility could be increased greatly with an ML that could recognise what was happening on the screen based only on the contents of say, the last few seconds of frame buffer data.
I’m also really excited for what AR (augmented with audio in particular) glasses and the like could do here too.
As for me, I'm partially sighted, so I learned to read print; I just need it larger and/or need to get up close to read it. So I can't contribute any first-hand knowledge or opinions on this topic.
When it comes to unemployment, I don't see how braille could help here. Half of the problem is employer bias, actual obstacles that are hard/impossible to overcome or artifical obstacles (inaccessible software) also matter. I think that solving the bias problem would make the situation much better, though. One more problem I see, at least here, is education. Blind people aren't really that aware of what they can realistically do, so they get majors in art, history, literature etc, or think they can get by without good education. No one tells them where to go to have a real chance of finding a job. Sighted people also do it, but, if nothing else works out, they can get a job at Wallmart/Mcdonald's. Blind people don't have that possibility.