This is true for strategic strike (a bomber has the space for crew rest) and an absolute godsend for the Navy (CVW have lacked real organic tank options since the retirement of the S-3- note that CVW ASW is another mission where drones could be dramatic improvements) but I don't think that this will enable something as dramatic as a pull-out of Al Udeid. No one is going to want to be in a F-22 or F-35 for a combat flight from Diego Garcia to Mosul, and US strategic strike components are so limited that I can't see them bearing the full burden of something like OIR.