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A comment on Study in mice explains how brain can turn pain signals up or down. Parent comment

Re:Study in mice explains how brain can turn pain signals up... by shakna on Wednesday October 16, 2019 @02:12AM (#21267556)
> Do these findings have any immediate practical benefit for humans?

Immediate? Probably not.

Practical? Probably yes.

There are quite a number of not-fully-understood chronic pain conditions out there. This likely offers some alternative approaches that may lead to more treatments, or even possible cures.

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Re:Study in mice explains how brain can turn pain signals up... by noir_lord on Wednesday October 16, 2019 @02:30PM (#21273750)
Neuropathic pain is an utter bastard to treat.

There are medications that are effective - gabapentin and pregablin (for some lucky people, me been one of them) but for others they aren't, Opiates don't do much neither do OTC painkillers - There is some evidence that Tramadol can help.

I'm glad we are continuing to make breakthroughs in the field even if it's a decade or two before they may show up, pain is an incredibly useful notification that something may be wrong except when the thing that is wrong the notification system as a whole.

I can cycle 60 miles, work all day etc but some days if someone steps on my foot I could drop them on the spot.

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