Still, they do specifically call out groups. I can't think of any that are actually safe or get a pass. I mean, they rag on Christianity and Judaism all the time. Then they do an episode harpooning and calling out atheists & Dawkins for being a bunch of assholes and make the case that religion isn't so bad.
I don't know if we'll ever see another South Park. Tight turn around times on episodes so their content is fresh and relevant. Best example of balanced opinion thus far... as a show where kids swearing and making fart jokes are the tame/mild highlights of the episodes... It's just... I think it's a straight up anomaly, not simply a unique situation. Seinfeld being as long running, successful and "sophisticated" show, that was unique. South Park said "hold my beer" to that and then shits in your hand just to get laughed at by a fat kid with an alien dish satellite popping out of his ass. And we are all okay with it!
We need more, not fewer South Parks.
Not that I agree with their every riff (being of the Evangelical ilk) but their irreverence is as American as the 1st and 2nd Amendments.
We either wear our South Park with pride, or become as Hong Kong or Venezuela or another country people are fleeing.