If you have multiple series, you could have different sounds running in parallel - sin wave, square wave or perhaps musical instruments each denoting a different series.
That might actually be usable if there was an automated system for creating them on the fly.
There's also this kind of approach https://www.youtube.com/watch?v=I9lquok4Pdk
https://www.highcharts.com/docs/accessibility/accessibility-... is a good starting point to learn more about the sorts of features and considerations they've made (you can find articles, demos, and videos describing more from there)
It offers a fast 5 minute scan for some of the most common/easily detectable issues, and also a much fuller assessment with a mix of automated checks and guided/assisted manual tests that aims to help web developers who aren't accessibility experts achieve full WCAG 2.1 AA compliance.
Happy to answer any questions about it!
EDIT: found this Web Accessibility Evaluation Tools List with 132 items listed! Anyone have advice on which ones are best?
https://www.w3.org/WAI/ER/tools/