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A comment on Talismans of Productivity: Or give up coffee.. Parent comment

Re:Talismans of Productivity: Or give up coffee. by pella on Thursday January 13, 2011 @09:12AM (#2099789)
"Some people get jumpy after drinking a single cup of coffee, while others can gulp down a Venti Americano without feeling a thing. Part of that variability is due to the development of tolerance by regular coffee drinkers; but there are genetic differences in how people metabolize caffeine as well. "

https://www.23andme.com/health/Caffeine-Metabolism/

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"Coffee, CYP1A2 Genotype, and Risk of Myocardial Infarction"

http://jama.ama-assn.org/content/295/10/1135.long

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