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A comment on Effect of High-Dose Vitamin D on Volumetric Bone Density and Bone Strength. Parent comment

Re:Effect of High-Dose Vitamin D on Volumetric Bone Density ... by ebg13 on Monday September 09, 2019 @04:08PM (#20921907)
> Headline is not imprecise according to above-cited Conclusions and Relevance.

No, aladoc99 is right, because the study doesn't compare against 0. So you don't know if 4000 and 10000 improve strength compared to 0, only that they don't compared to 400. It's not a hill that someone should die on, though.

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Re:Effect of High-Dose Vitamin D on Volumetric Bone Density ... by fc_barnes on Monday September 09, 2019 @07:48PM (#20923769)
Nobody has 0 intake, that is a useless control; nor would any IRB sign off on such a study, because it would be harmful to the subjects.
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Re:Effect of High-Dose Vitamin D on Volumetric Bone Density ... by ebg13 on Monday September 09, 2019 @07:57PM (#20923827)
> Nobody has 0 intake

And thus we have ourselves a quandary, but truth isn't diminished by the practical limits of safe experimentation. We don't have to lie just because.

> it would be harmful to the subjects.

That doesn't make the title precise or the observation inapt.

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Re:Effect of High-Dose Vitamin D on Volumetric Bone Density ... by scottlocklin on Monday September 09, 2019 @08:00PM (#20923852)
The experiment itself may be useless control; most people get D vitamins from the sun. How do we know the cohorts got the same D from sun exposure?
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Re:Effect of High-Dose Vitamin D on Volumetric Bone Density ... by AstralStorm on Tuesday September 10, 2019 @01:36AM (#20925307)
Should use a blood tests for vitamin D status, probably calcium, phosphate and K too instead of relying on self reported diet.
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Re:Effect of High-Dose Vitamin D on Volumetric Bone Density ... by slothtrop on Monday September 09, 2019 @07:53PM (#20923808)
If you avoid animal foods the only dietary vitamin D really is from fortified products. However we also synthesize it, albeit poorly as adults, particularly with lower exposure to the sun.
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Re:Effect of High-Dose Vitamin D on Volumetric Bone Density ... by kibibu on Monday September 09, 2019 @11:40PM (#20924844)
Plenty of people have 0 supplementation though.
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