prions are currently a problem for basically any equipment, but they are rare, and they are not this problem - this is an issue of basic sanitation of modern, intricate and difficult to sanitize devices causing bacterial infections.

Steris sterilizers (think sort of dishwasher-type devices with a highly specialized detergent) can do this, I believe. I'm pretty sure there's still room for error with devices that are complicated enough that they might not be completely cleaned by the flow of the cleaning chemical, which is a problem with almost any cleaning method you use on that kind of equipment.

Hypochlorous acid (HOCl).

https://www.heraldnet.com/business/scientist-woodinville-com...

Plasma probably. Again metal only.

High energy ultra violett light? Yes, it destroys plastics- and only reaches surface layers. But if you get it to the evaporation stage and keep it up long enough - cleansed is cleansed.