Re:Crispr now cuts and splices whole chromosomes
by gradys on Friday August 30, 2019 @05:05PM
(#20842705)
Thanks for the excellent and detailed reply! Are there any papers you recommend im particular? One of the harder parts of getting into a new domain of science is that it's hard to tell the good/important papers from the others.
[ Parent
| on HN ]
Re:Crispr now cuts and splices whole chromosomes
by aaavl2821 on Friday August 30, 2019 @05:27PM
(#20842885)
I'm not the best person to answer this, as I generally just read the stuff my friends send me, but here is the original CRISPR paper: https://science.sciencemag.org/content/337/6096/816
May also be interesting to read this paper on a gene editing tech, which ending up being irreproducible.
original paper: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6077703/
biorxiv manuscript showing science isnt reproducible: https://www.biorxiv.org/content/10.1101/704197v1
article summarizing the above papers: https://blogs.sciencemag.org/pipeline/archives/2019/07/26/vi...
Other labs that off the top of my head that are active in gene editing are Feng Zhang, David Liu, Matthew Porteus. Of course I am missing most of the important labs but these are some important players