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Re:Alternate Day Fasting Improves Physiological and Molecula... by goda90 on Tuesday August 27, 2019 @03:29PM (#20813547)
>For healthy, non-obese adults, ADF is safe to practice for several months

They might just be saying this because they didn't test any further, but does anyone know any reasons why it might stop being safe after several months?

Re:Alternate Day Fasting Improves Physiological and Molecula... by moltar on Tuesday August 27, 2019 @03:32PM (#20813578)
IMO it’s not unsafe. The longest supervised fast was a whole year long. The person was obese and only supplemented vitamins if I remember correctly.

Fasting is how we evolved to eat. We didn’t have Costco and fridges 10k years ago.

Re:Alternate Day Fasting Improves Physiological and Molecula... by javagram on Tuesday August 27, 2019 @03:44PM (#20813694)
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2495396/

Note, however, he died relatively young although he did live a few decades after the fast https://en.m.wikipedia.org/wiki/Angus_Barbieri%27s_fast

Re:Alternate Day Fasting Improves Physiological and Molecula... by simcop2387 on Tuesday August 27, 2019 @03:49PM (#20813754)
I'm not aware of any specific reason why it'd become unsafe over long periods of time, but just getting regular checkups and talking with a doctor should be enough to identify it in an individual.

While not nearly as scientifically rigorous as this study there's a lot of people out there who do a more general form of this and call it "intermittent fasting". Usually things ends up as a complete restriction on calorie intact except during designated times, 16:8 or 18:6 are common forms of it where you're fasting for 16 or 18 hours a day, and can only eat during those other 8 or 6 hours. You still have to limit your calorie intake (eating 5,000 calories in 6 hours still isn't going to do anything good for your health). And some people take it even more to an extreme with what they call OMAD or One Meal A Day.

This kind of study looks like it points to some of the claims that this kind of diet could have actual benefits aren't entirely unfounded. I've doubted most of the claims I've seen people make since they largely seem completely fanciful and not had any real testing or study done on them but still plan to try to adhere to a diet like this simply because it looks like it should help deal with self-control and discipline issues that I know I have when it comes to food.

Re:Alternate Day Fasting Improves Physiological and Molecula... by Havoc on Tuesday August 27, 2019 @03:37PM (#20813649)
Doubtful. Humans aren't that fragile...a day hardly matters.

...drink water though

Re:Alternate Day Fasting Improves Physiological and Molecula... by javagram on Tuesday August 27, 2019 @03:45PM (#20813711)
You might lose too much weight. Depending on your diet I could see it being hard to maintain a healthy weight on a lifelong regimen of ADF.
Re:Alternate Day Fasting Improves Physiological and Molecula... by geoka9 on Tuesday August 27, 2019 @03:33PM (#20813594)
I could think of gallstone disease, but I'm not a doctor.
Re:Alternate Day Fasting Improves Physiological and Molecula... by goldemerald on Tuesday August 27, 2019 @03:48PM (#20813736)
Specifically, here's the relevant text from the paper:

"...extended overnight fasting periods might increase the risk of gallstone disease (Sichieri et al., 1991)"

Re:Alternate Day Fasting Improves Physiological and Molecula... by lazyguy on Tuesday August 27, 2019 @03:55PM (#20813815)
Par for the course on any sort of diet that has fairly high weight loss.