We use PurgeCSS[0] as part of our build process to remove all of the Tailwind classes that weren't used. That gives our developers the freedom to work/experiment with everything Tailwind has to offer while spitting out super tiny and optimized CSS files.

I just checked one of our more recent projects and the resulting CSS is 2.4KB, about half of which is actually an SVG that's used in a background.

[0] https://www.purgecss.com/