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Re:“Evidence-based medicine has been hijacked”: John Ioannid... by newcrobuzon on Friday July 05, 2019 @04:21AM (#20360776)
It is a sad reality that some of the regulatory agencies have been captured by the industry groups. This is especially concerning in healthcare and pharma industry. Take for example Vioxx and Opioid issues: Merck Manipulated the Science about the Drug Vioxx - https://www.ucsusa.org/manipulating-science-about-drug-vioxx Purdue infiltrated WHO, manipulated opioid policies to boost sales, report finds - https://arstechnica.com/science/2019/05/world-health-organiz...

Yet it is still surprising to see that on HN in general anyone questioning safety of pharmaceutical products get downvoted into oblivion.

Re:“Evidence-based medicine has been hijacked”: John Ioannid... by Madmallard on Friday July 05, 2019 @08:05AM (#20361863)
It's way worse than that. Fluoroquinolone antibiotics are well known in research for being seriously dangerous yet they were prescribed like candy for over a decade. So many people develop disabling symptoms overtime that end up not being linked to the drug because dna adduction and mtdna depletion won't necessarily show up quickly. The drugs have likely disabled hundreds of thousands at this point by Dr Bennett's estimations at UNC. There's something like 10,000 reports and those are assumed at being less than 10% and possibly 1% of total incidents.