You can reverse intestinal permeability though diet. However, there is no money in it and neither is it a complicated treatment. Thus, the papers about it won't get published in prestigious journals.
Re:What Is the Human Microbiome, Exactly?
by Nuzzerino on Saturday June 29, 2019 @10:46PM
(#20316045)
I'm curious to know much the journal prestige actually factors in to the odds of the described medical technique eventually becoming a usable clinical practice. I wonder if anyone has done that kind of analysis and published results.
Re:What Is the Human Microbiome, Exactly?
by Madmallard on Saturday June 29, 2019 @08:26PM
(#20315681)
[citation needed]
Brain Maker: The Power of Gut Microbes to Heal and Protect Your Brain for Life by Perlmutter
I have a theory that fad diets like keto, paleo, primal blueprint, low fodmap, whole 30 (of which there are numerous people claiming they have major improvements) really work because they influence the gut biome.
Re:What Is the Human Microbiome, Exactly?
by throw345hn on Saturday June 29, 2019 @09:20PM
(#20315802)
I cant speak for other diets but I follow low fodmap diet as I suffer from IBS. I always assumed that I was prescribed that diet to influence the gut bacteria. I mean the bacteria ferment on high fodmap foods and bloat and distend your stomach.
Talking about low fodmap specifically I wouldnt call it fad as it has been and is being researched and has shown to be effective to help with IBS, maybe not so much for other conditions.
Personally I have found it helpful in reducing the symptoms that I have.
Re:What Is the Human Microbiome, Exactly?
by Madmallard on Sunday June 30, 2019 @08:11AM
(#20317793)
https://www.thecut.com/2015/06/problem-with-the-grain-brain-...
:thinking:
I don't know about this guy. I got that link from quackwatch.
Re:What Is the Human Microbiome, Exactly?
by rorykoehler on Saturday June 29, 2019 @09:42PM
(#20315880)
Keto is working for me to treat AS specifically for this reason. Had to experiment a long time to find the right diet. If I stray I flare up pretty quickly.
Re:What Is the Human Microbiome, Exactly?
by atombender on Saturday June 29, 2019 @08:11PM
(#20315638)
Interesting. Links?
It's been known for a while that some gut disorders, including Crohn's, can manifest as skin lesions of various kinds, and bowel bypass patients can also develop skin symptoms. It's also known for a while that autoimmune patients have less bacterial diversity in their gut, and an increased abundance of certain types of bacteria, especially in the small intestine. Research has found that in such patients, gut bacteria can migrate from the gut to the bloodstream and then to the skin. Psoriasis patients, for example, have a much higher gut permeability than non-psoriatics (not to be confused with the pseudoscientific Internet hysteria around "leaky gut"!) and have deficient bile acids.
Treatment would involve resetting the gut somewhat by eradicating the known pathogens. Astonishingly, a Hungarian study in 2003 [3], which used an experimental treatment with bile acid supplementation, was able to completely clear psoriasis in 78% of its subjects (even more in a second, more acute group), which is unheard of, and about 58% were still clear 2 years later. I don't know why that study hasn't revolutionized things; it's only been cited 11 times according to Scopus.com.
[1] https://www.ncbi.nlm.nih.gov/pubmed/29908580
[2] https://www.nature.com/articles/nrmicro2974
[3] https://www.sciencedirect.com/science/article/pii/S092846800...