AFAICT, there's not much definitive research that shows the harms of cannabis consumption. I'm aware of the research that clearly counterindicates usage by teenagers and young adults due to continued brain development issues, but is there evidence that cannabis consumption is unhealthy otherwise?

I think even the larger cohort studies failed to connect joint smoking with ear/nose/throat/lung cancer, much to the consternation of people who like to throw down the "combusting and inhaling anything has to be bad for you" statement.

Nor is it an 'alcohol replacement' :/