It can’t. At best you can try to modify the hosts file to point localhost to somewhere bogus, but aside from the potential breakage that could cause, it won’t help against any site that simply accesses http://127.0.0.1 instead of http://localhost. In general, the hosts file can be useful for quick-and-dirty blocking, but it’s not really capable of enforcing a security barrier.

Edit: But there may be other ways to do it at an OS level, depending on your OS.