It also seems you are self-deprecating. You must have some value - you were not paid for doing nothing!
But maybe what was found valuable in you by corporate america differs from what you define as a value.
Have you tried reading philosophy? It helped me. If philosophy is not your thing you can try more accessible literature. My biased suggestion would be Atlas Shrugged.
I would also suggest trying to define your life values (what's important for you?) and following that, defining your life goals (where do you want to make a chance?) - then it's "just" a matter of implementation.
Try lesswrong and transhumanist websites if that's your thing. Or anything else - it's your tastes that matters.
As many others pointed in the thread, anomie is best fought if you create your own meaning. To me, this meant defining my own values first.
Again, I might just need an attitude change, or I'm wearing the wrong glasses.