Again, I might just need an attitude change, or I'm wearing the wrong glasses.
It also seems you are self-deprecating. You must have some value - you were not paid for doing nothing!
But maybe what was found valuable in you by corporate america differs from what you define as a value.
Have you tried reading philosophy? It helped me. If philosophy is not your thing you can try more accessible literature. My biased suggestion would be Atlas Shrugged.
I would also suggest trying to define your life values (what's important for you?) and following that, defining your life goals (where do you want to make a chance?) - then it's "just" a matter of implementation.
Try lesswrong and transhumanist websites if that's your thing. Or anything else - it's your tastes that matters.
As many others pointed in the thread, anomie is best fought if you create your own meaning. To me, this meant defining my own values first.