I've done a hobby project where I'm using pure RPi GPIO to drive a servo motor with PWM, so processor interrupts would ruin my day. So I can tell you that the rate at which modern Linux interrupts a running application is massively overstated. If your system is configured right, that happens maybe two or three times a second at most.

If you're running on a dedicated core, as you should, 99% of the time your application just happily runs along.