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Re:Possible blood test for colon cancer by konschubert on Saturday April 27, 2019 @05:23AM (#19764676)
Are we sure that early detection really improves survival times or does it just look like this in the statistics because we detect the cancers in an earlier stage?
Re:Possible blood test for colon cancer by melling on Saturday April 27, 2019 @08:26AM (#19765175)
According to Craig Venter, early detection is what we need to eliminate cancer: https://youtu.be/iUqgTYbkHP8?t=15m37s
Re:Possible blood test for colon cancer by IfOnlyYouKnew on Saturday April 27, 2019 @06:37AM (#19764867)
This is a weird use of the standard trope about cancer survival rates improving being just a statistical artifact caused by early detection.

...because that (somewhat overdone) narrative already presupposes higher survival rates for cancers that are detected early.

Re:Possible blood test for colon cancer by tialaramex on Saturday April 27, 2019 @07:09AM (#19764940)
It depends upon a fact about what we mean by survival rates.

In most cases survival is defined in terms of fraction of population who are alive after a set period of time from diagnosis.

Suppose Bob is going to die of Foozle cancer in 2025. If I diagnose Bob in 2019 he gets more than five years survival. If my diagnosis method only catches it in 2023 the survival rate looks much worse. But all that changed is when I told Bob he's going to die.

In contrast if I develop a treatment for Foozle cancer, maybe Bob doesn't die until 2030. He's survived more than five years after diagnosis again - but this time it's because I was able to actually help.

Re:Possible blood test for colon cancer by imtringued on Saturday April 27, 2019 @09:15AM (#19765332)
You're forgetting a much simpler scenario that could wildly throw off survival statistics: early detected cancer might have a chance of never actually killing the patient even without treatment. Therefore early detection increases survivability in the statistics because it's counting more "duds".