Broken down a different way, you need two systems: an automatic system so you're not reconsidering decisions that have good outcome (a checklist), and a considerate system that decides what goes into or out of the automatic system.
If the considerate system is broken or just frozen, then you have a problem. How long it will take to manifest is a different question.
Removing an item from a checklist is done in response to a change in inputs. Sure, you may have automated release signing - but unless you are 100% confident that you are aware, and have mitigated 100% of the ways in which this can fail, you cannot, and should not remove the 'check that the release is signed' step.
Lost context has nothing to do with this. Unless you are an omniscient god, you probably cannot reason, with 100% certainty, that you have mitigated every possible input that produced a bad output.
So, check your outputs.
Having long checklists for comparatively simple tasks really hurts productivity, plus they're often used as an excuse to put automation in place, because 'the process is already defined' and 'people are already used to it'.
When designing a process, it is of utmost importance to keep checklist lengths minimal.
As the Boeing 737 Max 8 shows, adding new items (in this case a new design element) is also fraught with risks. You have to get the root analysis correct when adding or removing elements. Adding has risks of unknown (not accounted for) like removing has risks of unknown (accounting forgotten).
In the end, I guess I still believe the best strength is in good analysis at the consideration stage.
The asymmetry with checklists is that it's completely risk-free to add a new check, but it's risky to remove one. For example, someone might say "we're not totally sure that our system won't fail when we do X, so let's check that in QA, or at runtime, or at takeoff, or whatever." Now that the check is there, it protects you from failures when you do X. And now you're in a situation where you can't safely remove that from the checklist unless you can prove that your system won't fail when you do X. Adding requires only a suspicion, removing requires rigorous proof.
The case you describe with the 737 Max isn't the same at all. There's an actual risk when adding a new component to the system, but no risk when adding additional verification. That's not to say that there aren't other costs, but it can't directly make your system less reliable.
It's not a risk free check at all. It will likely increase the rate at which the drug is administered, with all types of plusses and minuses associated with adding a component to a system.
So disruption is taking a bulldozer, and driving right over them. The clearly usefull fences get erected quickly. The forgotten usefull ones are rediscovered after a while, maybe causing some minor damage in the process. But the grand majority turned out to be useless, and is now gone for good.
Of course, if there is a pack of nuclear civilization killing wolves out there, they better stay fenced off or else. The trick is identifying them. There might be a role for a regulator in there.
[0]: https://medium.com/war-is-boring/u-s-navy-supercarriers-domi...