News for hackers. Stuff that matters.
Re:Gene Therapy Was Hailed as a Revolution – Then Came the Bill by Mirioron on Monday April 08, 2019 @02:18AM (#19602589)
It's ethical, because as a society we need to look at the long term rather than any specific treatment. It's better for us if private investors invest money into lifesaving treatments, because it means that more of them will be available earlier to people. If investors go and invest in something else then nobody's getting the benefit of the medicine.

Let's say we have a disease that kills 1000 people per year. Let's look at a 40 year period.

1. No cure is researched or found in 40 years. Total death count: 40,000.

2. For the first 10 years no cure is found. After 10 years a company comes along and creates a lifesaving cure, however it's expensive - only 500 people per year can afford it. The patent on it lasts 20 years. After 20 years another company creates a generic version of it that 990 people can afford. In the first 10 years 10,000 people die, in the following 20 years another 10,000 people die, in the last 10 years 100 people die. Total death count: 20,100.

3. No cure is found in the first 20 years, then a government funded research team finds a cure. A company picks it up and creates a generic, where 99% people can afford it. In the first 20 years 20,000 people die. In the latter 20 years 200 people die. Total death count: 20,200.

Being early matters in medicine. It's always easy to look at an expensive treatment and say that this should be much cheaper, but we usually don't consider that forcing investors out of healthcare means that less research will be done. This means fewer treatments and a longer time before a treatment is found.

Re:Gene Therapy Was Hailed as a Revolution – Then Came the Bill by ordu on Monday April 08, 2019 @06:33AM (#19603879)
I like your comment, it explains a lot. It seems that the system was built the way, that makes a drug research to grow a pie, while in an ideal world where everyone is happy and everything is fair, drug research would shrink the pie: it is the goal of medicine to eliminate all diseases. It means, that all that system is working on self-destruction, but we allow them to get excessive profits now, to make it work.

There is only one detail I cannot understand. Why competition doesn't work? Why some new investors (who are not invested in drugs yet) do not invest in the research of new drug that heals all the diseases, to sell this drug for $1 -- they would destroy existing system, but they would get all the market at once. (Or in a smaller scale they might make a drug that treats some disease once and for all, and shrink not the pie overall, but some part of it).

Re:Gene Therapy Was Hailed as a Revolution – Then Came the Bill by nradov on Monday April 08, 2019 @09:25AM (#19604921)
Competition does work. You can see that by looking at the average profit margins for drug companies: they aren't particularly high. The problem is that drug development is just really hard and expensive. All the low hanging fruit has already been picked.
Re:Gene Therapy Was Hailed as a Revolution – Then Came the Bill by contravariant on Monday April 08, 2019 @04:38AM (#19603303)
I mean if we're only looking at made up numbers anyway isn't the 3rd scenario preferable? Almost the same number of people died, but there was no 20 year long period where people were paying extortionate rates for a medicine, and it took 30 years before the diseases was effectively cured, as opposed to the 20 years it took before a government funded cure came along.

You might even argue that the money saved by not having a patent could be used to save even more lives.

Re:Gene Therapy Was Hailed as a Revolution – Then Came the Bill by wetpaws on Monday April 08, 2019 @05:41AM (#19603640)
It's preferable until it's your own head on chopping block.
Re:Gene Therapy Was Hailed as a Revolution – Then Came the Bill by luma on Monday April 08, 2019 @06:15AM (#19603790)
...and you also happen to have money.
Re:Gene Therapy Was Hailed as a Revolution – Then Came the Bill by ludston on Monday April 08, 2019 @03:22AM (#19602910)
I invent another imaginary hypthetical situation:

4. Nobody makes any attempt to create a treatment, but after only six months a miracle occurs. Nobody dies and everybody is cured for no reason.

Not saying that there isn't any, but where is the evidence that a government funded research team would be slower than the privately funded one?

Re:Gene Therapy Was Hailed as a Revolution – Then Came the Bill by Mirioron on Monday April 08, 2019 @03:58AM (#19603096)
The problem isn't that a government funded research team is slower, it's that the private research team is in addition to the government research team. There are an uncountable number of illnesses and conditions that treatments could help with, but we have only so many resources to throw at these problems. Additional resources will allow us to find treatments for problems that we couldn't afford to research otherwise.

If the government invests $100 billion into medical research and private companies invest another $100 billion then we're probably getting more medical research done than if only the government invested $100 billion into medical research, and the private companies spent the $100 billion on making movies.

Re:Gene Therapy Was Hailed as a Revolution – Then Came the Bill by Jweb_Guru on Monday April 08, 2019 @03:38AM (#19603002)
Considering that many effective research teams are government funded, I suspect there is essentially no evidence of that.