Smell/organic chemistry is weird, too. Some molecules have similar smells, despite being sometimes quite different. Many molecules have quite different smells, despite being not that different [0], edit: the esters table maybe shows that better, [1].
[0] https://jameskennedymonash.wordpress.com/2014/01/04/table-of...
[1] https://jameskennedymonash.wordpress.com/2013/12/16/infograp...
For the helium leak, is one symptom a high squeaky voice, or is that at already really dangerous concentrations?
This happened also to the coworkers of a friend of mi e - occasionally everyone's iPhone in their office would stop working. Android phones still worked fine. Later (after this article was published) they found out there was an MRI machine downstairs.
Also noses self repair. You can foul them with another scent for a while but eventually the receptors will recover.
Edit: for the difficulty of machine chemistry, see also the Theranos debacle.