Microsoft, UW demonstrate first fully automated DNA data storage

Re:Microsoft, UW demonstrate first fully automated DNA data ... by KallDrexx on Saturday March 23, 2019 @08:44AM (#19470214)

Does anyone know how they ensure read order? Since it's a fluid that's moving around I'm having a hard time to grasp how they make sure they read the DNA in the same order it was written in.

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Re:Microsoft, UW demonstrate first fully automated DNA data ... by mbreese on Saturday March 23, 2019 @08:55AM (#19470249)

You wouldn’t. The read order would be encoded in the “file format”. Kind of like a Unicode byte order marker.

You’d have to deconvolute the signal first, then computationally determine the strand you actually read.

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Re:Microsoft, UW demonstrate first fully automated DNA data ... by shpongled on Saturday March 23, 2019 @11:55AM (#19470939)

DNA polymerase "reads" in one direction, so you prime the polymerase with a short DNA sequence (a primer), that is complementary and located 5' (before) the section you want to read

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Re:Microsoft, UW demonstrate first fully automated DNA data ... by iso1337 on Saturday March 23, 2019 @10:41AM (#19470631)

Related is querying: You can synthesize another pair of Oligos to selectively amplify part of the DNA that you wrote and only sequence that. Look up PCR if you are interested.

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Re:Microsoft, UW demonstrate first fully automated DNA data ... by adjkant on Saturday March 23, 2019 @03:37PM (#19471988)

When reading this it made me wonder if DNA storage will borrow a lot of concepts from SIMD

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