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Re:Longevity and anti-aging research: ‘Prime time for an imp... by sanxiyn on Tuesday March 19, 2019 @04:24AM (#19428999)
This is a great news. Fighting aging is one of the most important challenge of our time.

This is also encouraging:

"Gazette: Are there regulatory hurdles? When we've spoken in the past, you've mentioned that the FDA considers aging a natural process and therefore won't approve drugs to treat it.

Sinclair: I've been part of a group that talked with the FDA, and they are willing and also quite enthusiastic about considering a change that defines aging as a disease."

Re:Longevity and anti-aging research: ‘Prime time for an imp... by guzik on Tuesday March 19, 2019 @04:43AM (#19429076)
Aging is a disease, there should be no doubt in that. What makes aging unique is that it affects 100% of the population.
Re:Longevity and anti-aging research: ‘Prime time for an imp... by lm28469 on Tuesday March 19, 2019 @05:11AM (#19429204)
That's also the only thing that keeps our population in check.

Let's see how we handle the incoming retirement issues, that'll give us a good indication (less workers, more retired people pretty much everywhere in the west, peaking in the next few decades).

Living long won't help much if it just means more people consuming our limited natural resources and weighting on our social infrastructure. At any rate most country would shift their retirement age accordingly and life would be the same but longer, I fail to see the appeal of that (albeit it's the ultimate realization of our "us vs nature" western mentality)

We should figure how to live well before we try to live longer, and we still have some things we're nowhere close to figure out (energy, pollution, retirement, increasing pop, &c.)

But all of that only applies if everyone has access to this tech, which I doubt. Most likely it will be a "cure" for the rich.

Seems to me that scientists are working toward goals that kind of look nice on paper (curing aging, genetic modifications, &c.) without stopping even one second and thinking about the moral/social/economical consequences down the line.

Re:Longevity and anti-aging research: ‘Prime time for an imp... by Nasrudith on Tuesday March 19, 2019 @03:50PM (#19434971)
I suspect the opposite given history. Humans are very reactive to incentives - more deaths leads to more reproduction so that when threats are gone they stop trying to "out-compete" it. The deadliest wars in history failed to make a dent but peaceful first world nations are leveling off to replacement rate or worse or only achieving it through immigration. Furthermore living long encourages even the selfish to care more about sustainability since "whatever I'm not going to be around for it" wouldn't be a thing.

As for "only the rich" there are only two kinds of tech roll outs - cheaper alternatives to the existing or for the rich first. The previous while impactful tends to be less groundbreaking by definition because it isn't anything "novel". The latter is how it always has been.

We always here "but what about the consequences" but I have yet to hear a proper forecast. Which means it ammounts to stopping development for imaginary fears, pointless. The time to stop is if there are problems in testing /after it actually exists/.

It is one thing to say cancel carbon nanotube body armor or structural components due to being too carcinogenic - it is another to stop development for fear it will somehow create a new ice age, grey goo, or similar.

Re:Longevity and anti-aging research: ‘Prime time for an imp... by jamesrcole on Tuesday March 19, 2019 @06:02AM (#19429431)
> That's also the only thing that keeps our population in check

Thinking longer-term, it's that plus being restricted to a single planet.

Before anyone says being multi-planetary is a pipe dream, it's historically true that what ends up happening in the longer-term tends to always to be something that would have seemed ridiculous and unrealistic at the time.

Of course, there's all sorts of questions here of the practicalities (eg costs) and the timeline (eg life extension could happen well before being multi planetary).

My primary point is only that it's not necessarily true that death will always be the only thing keeping the population in check.

Re:Longevity and anti-aging research: ‘Prime time for an imp... by saiya-jin on Tuesday March 19, 2019 @09:06AM (#19430366)
Not only that, longevity might be proper route to hell for mankind - take the worst dictators, what would they achieve with much longer time on earth. Psychopaths in power don't get better with age, do they.

Generally as with any powerful new tech, inventors/scientists fail to anticipate worst possible usage for it, which is how it will be (also) used.

There would be no way to anyhow regulate it, people would go to great lengths to get it (just look how some are OK with driving animal species extinct just to get potence medicine which is proved to be not working).

Don't get me wrong, I don't think we can avoid it, but it will bring some nasty consequences before it will become a net gain for mankind.

Re:Longevity and anti-aging research: ‘Prime time for an imp... by milimetric on Tuesday March 19, 2019 @02:17PM (#19433791)
Maybe people are psychopaths because something goes wrong with their cells, and this research will cure that. Can’t know anything like what you or I are suggesting, but we shouldn’t always guess pessimistically.
Re:Longevity and anti-aging research: ‘Prime time for an imp... by est31 on Tuesday March 19, 2019 @10:26AM (#19431083)
With that kind of argument, you could also say that our current situation is proper route to hell because psychopath babies are being born constantly, or idk joung people becoming psychopaths or however that works. Sure often, once a psychopath is in power, waiting for them to die of a natural cause is the easiest way of removing them. And surely, if you take the most cruel ruler each country ever had, put them into power right now, and made them never die, it would be proper hell. But that scenario is entirely artificial. Currently, and throughout history, most people in power aren't cruel psychopaths of the likes of Stalin and Hitler. We just remember the cruel ones more than we remember the boring non-cruel ones.

Unless in an aging-free world, for some reason non-psychopaths are more likely to give their power to psychopaths than the other way round, I think we don't need to worry.

Re:Longevity and anti-aging research: ‘Prime time for an imp... by ionised on Tuesday March 19, 2019 @05:53AM (#19429396)
Don't worry, poor people will still age and die.
Re:Longevity and anti-aging research: ‘Prime time for an imp... by xiphias2 on Tuesday March 19, 2019 @08:13PM (#19437556)
Do you realistically think that it will not be worth to scale the solution?

Many medications stay expensive because not big enough number of people are affected. Also don't think U.S. only: how do you stop people from going to China to get the cheap (but well tested) copy of a medication?

Re:Longevity and anti-aging research: ‘Prime time for an imp... by lm28469 on Tuesday March 19, 2019 @06:43AM (#19429618)
We'll make a lesser version of it available to everyone who gets a mortgage > 50 years and a new electric car. It'll involve weekly injections though, that way as soon as you stop paying you go back to where you belong.
Re:Longevity and anti-aging research: ‘Prime time for an imp... by netsharc on Tuesday March 19, 2019 @04:40AM (#19429060)
And not climate change? In my mind's model of the future we're going to die within 50 years, this research is useless when the infinitely aged doesn't have clean water to drink.
Re:Longevity and anti-aging research: ‘Prime time for an imp... by Erlich_Bachman on Tuesday March 19, 2019 @04:53AM (#19429132)
One of the main connections to longevity people usually miss in this whole "climate change" discussion is one of the main psychological reasons people don't take care of the environment in the first place: and it's arguably their lifespan. Everyone in the west knows that they will die at most ~100 years of age, and if you are basically not in some top percentile morality-wise (and also at that point in your life where all more important problems are resolved and you even have energy to care about the environment), you just don't care about it because you know you're going to die anyway. Of course many people think about their children and the other people etc, but many don't.

If we manage to extend the expected (or even just possible) generic lifespan of normal people - that will be one of the best promoters of environment-thinking of normal population. Because suddenly the choices they make today become very real in terms of impact on the environment in the next 50-100-200 years, because there is a good change that this same person is going to be living at that time.

Re:Longevity and anti-aging research: ‘Prime time for an imp... by lm28469 on Tuesday March 19, 2019 @05:37AM (#19429313)
But that's two sides of the same coin, individualism.

Even if we lived 120 years in average, do you think the game would change a lot, I don't. I don't see drastic changes in young people today, yet they'll most likely be alive in 60-70 years. And for argument's sake, even if it does we still end up with much more people living on the same resource limited planet at the same time.

You can already bump your life expectancy (and end life quality) quite a lot by eating health, exercising, quitting drinking/smoking. Most people don't do it because it's too much effort and "that's not life", again individualism/short sightedness.

We need a cure for laziness / individualism, then, maybe, we can start talking considering longevity.

Re:Longevity and anti-aging research: ‘Prime time for an imp... by Erlich_Bachman on Tuesday March 19, 2019 @07:30AM (#19429812)
> because it's too much effort

This is exactly the reason these scientists are focusing on genetic and other medical ways to increase lifespan, which are going to be packaged in products that can be used without effort. One might say what they want about people not wanting to expend unnecessary effort, one might call it lazy or just smart, or a drive of progress, it doesn't matter. The fact is if you give people a method that requries less effort, more people will use it. Thus we will have a greater general effect on the population with these methods.

Re:Longevity and anti-aging research: ‘Prime time for an imp... by lm28469 on Tuesday March 19, 2019 @09:32AM (#19430617)
But again, what's the goal ?

Giving lazy people the opportunity to continue living lazily longer while ravaging the planet ? Welcome to transhumanists paradise I guess.

Re:Longevity and anti-aging research: ‘Prime time for an imp... by LinuxBender on Tuesday March 19, 2019 @04:37PM (#19435541)
I imagine that governments would want to squeeze more taxable years out of people and bump the retirement age to 85 or higher.
Re:Longevity and anti-aging research: ‘Prime time for an imp... by tomp on Tuesday March 19, 2019 @05:32AM (#19429292)
No the main psychological reason is that people are bad at rationally assessing risks. E.g. most fear flying more than driving.

Then there's also other (more economical, but you could say that's caused by psychology as well) reasons, such as tragedy of the commons.

Re:Longevity and anti-aging research: ‘Prime time for an imp... by Erlich_Bachman on Tuesday March 19, 2019 @07:28AM (#19429798)
Perhaps a bit OT, but it is interesting that people keep bringing fear of flying as "irrational risk".

People fearing flying more than driving are not afraid of the relative chances of dying (which are low either way). They are afraid of the feeling and experience of spending long time in a falling plane knowing that you are going to die, being stuck in one seat and not being able to do anything about it. This does not happen when you are driving, if there is an accident, you usually either die instantly or in some rare cases receive some injuries, but at least then you can lie at the site of the accident and hope that medics will come. It's not the same as being stuck in a box for 10s of minutes knowing you are most likely about to crash to a painful death. You have to spend time in that experience, to feel it, in a completely hopeless state. That's why people afraid of flying, not because of some statistics.

Re:Longevity and anti-aging research: ‘Prime time for an imp... by tomp on Tuesday March 19, 2019 @07:30AM (#19429804)
Haha I was pondering the same line of thought just 2 days ago (while I was on an airplane).
Re:Longevity and anti-aging research: ‘Prime time for an imp... by kristofferR on Tuesday March 19, 2019 @04:51AM (#19429118)
If "old people" weren't sure they would die within the next 30 years anyway, then perhaps they would actually start caring about the planet.
Re:Longevity and anti-aging research: ‘Prime time for an imp... by jhayward on Tuesday March 19, 2019 @08:17PM (#19437582)
As an "old person" this feels personal. What evidence do you have that supports such a claim for "old people"?
Re:Longevity and anti-aging research: ‘Prime time for an imp... by kristofferR on Wednesday March 20, 2019 @05:08AM (#19440270)
https://news.gallup.com/poll/234314/global-warming-age-gap-y...

Only 29% of Americans over 55 think climate change will pose a serious threat in their lifetime :(

Re:Longevity and anti-aging research: ‘Prime time for an imp... by jhayward on Wednesday March 20, 2019 @05:47PM (#19447319)
That's a cherry-picked stat if I ever saw one. In context of this thread you seem to be equating that with "think climate change is a problem that needs to be addressed", which is an entirely different question. Most of us don't want to see our kids lives ruined.

In fact, the headline stat of that linked survey is "56% of Americans over 55 worry a great deal about global warming".

Re:Longevity and anti-aging research: ‘Prime time for an imp... by guzik on Tuesday March 19, 2019 @04:45AM (#19429086)
That's why he said "one of the most important challenge".