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Re:Herpes Virus Reactivation in Astronauts During Spaceflight by mfoy_ on Monday March 18, 2019 @02:25PM (#19423653)
It's well known that stress weakens the immune system[1]. So it's not a surprise that stress might encourage dormant infections (such as HSV-1) to enjoy a resurgence.

[1] https://www.apa.org/research/action/immune

Re:Herpes Virus Reactivation in Astronauts During Spaceflight by dajohnson89 on Monday March 18, 2019 @06:52PM (#19426164)
I get canker sores [0] only during periods of extremely high stress or sleep deprivation.

[0]https://en.wikipedia.org/wiki/Aphthous_stomatitis

Re:Herpes Virus Reactivation in Astronauts During Spaceflight by jacobolus on Monday March 18, 2019 @05:25PM (#19425481)
Speaking anecdotally, sleep deprivation is the biggest immune system damper for me. Often it’s hard for me to judge the effects of stress per se, because sleep deprivation also leads to stress and vice versa.