It messed up the network-manager/DNS iirc, though this was a while ago as I mentioned. The problem had something to do with the configuration of the Ubuntu package which was kinda fucked up so that didn't help matters, this is pre-16.04 so I'm hoping it got sorted out later on.
I've been using it on OS X / macOS for years. Occasionally I'd run into an ISP that blocked it or a resolver that was slow or down but the software was always solid.