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Re:Ketamine Could Soon Be Used to Treat Suicidal Ideation by gnulinux on Tuesday February 05, 2019 @01:02PM (#19087769)
Sorry, but this bizarre. Psychotherapy is just one tool in the toolbox against treating mental illnesses. If there is evidence this drug helps treating mental illnesses, what's the reason not to use it? This is not some alternative medicine that is offered instead of or in addition to scientific practice. This is part of the usual treatment that involves psychotherapy, if it's useful. There is nothing inherently bad with drugs; you don't hesitate to use drugs when your liver chemistry breaks, why hesitate it when your brain chemistry breaks?
Re:Ketamine Could Soon Be Used to Treat Suicidal Ideation by nickbarnwell on Tuesday February 05, 2019 @01:52PM (#19088440)
The problem is that the effect sizes for most anti-depressants is quite small and the role of pharmaceutical companies in advancing their use has been quite a bit larger. The difference between psychotherapy and medication and psychotherapy alone is small.

I would also point out that dialysis, chemotherapy, etc are also quite expensive, time consuming, and difficult to scale. We still consider them valid, life-saving treatments.

Re:Ketamine Could Soon Be Used to Treat Suicidal Ideation by cc-d on Tuesday February 05, 2019 @03:41PM (#19089593)
>The problem is that the effect sizes for most anti-depressants is quite small and the role of pharmaceutical companies in advancing their use has been quite a bit larger. The difference between psychotherapy and medication and psychotherapy alone is small.

Ketamine is not your traditional SSRI. You're making the same error as the other poster in grouping all "antidepressants" under the same umbrella, which is particularly egregious when discussing ketamine.

Re:Ketamine Could Soon Be Used to Treat Suicidal Ideation by nickbarnwell on Wednesday February 06, 2019 @03:54PM (#19099836)
I am referring to traditional agents, not ketamine. There is insufficient evidence to draw conclusions about Ketamine's usefulness as a rapidly acting agent for treatment of depression.

I lack training in psychopharmacology or neuroscience and thus my interpretation of the research is that of a layperson, but my understanding from talking with psychiatrists on the matter is that it is unlikely that ketamine will become a frontline treatment but its mechanism of action will be explored and lead to the development of new drugs that activate the same pathways in the brain but lack or have lessened anesthetic effect.

Re:Ketamine Could Soon Be Used to Treat Suicidal Ideation by faissaloo on Tuesday February 05, 2019 @02:03PM (#19088566)
You don't use a nuke if you only need to kill one guy. I'm not against it being used but we need to be careful, we don't want another opiod crisis.
Re:Ketamine Could Soon Be Used to Treat Suicidal Ideation by gnulinux on Tuesday February 05, 2019 @03:11PM (#19089268)
I think opioids are in a very special spot. There are very few drugs that are as intensely addictive and as harmful as opioids and are used in medical profession. In particular, ketamine is nowhere near as addictive or harmful as opioids. Your point is valid, we should be careful, but we should also recognize the special status of opioids.
Re:Ketamine Could Soon Be Used to Treat Suicidal Ideation by cc-d on Tuesday February 05, 2019 @03:48PM (#19089684)
>I'm not against it being used but we need to be careful, we don't want another opiod crisis.

This is a horribly ignorant statement. Ketamine therapy is in no way comparable to widespread opioid prescription in risk. You are once again comparing drugs with entirely different mechanisms of action.