There is a discussion about Instagram's approach to migrating to python3 around the 34 minute mark in this talkpython podcast
https://talkpython.fm/episodes/show/155/practical-steps-for-...
Lisa Guo's presentation starts around the 13 minute mark in the 2017 keynote linked to on that page.
Here's a blog post about Dropbox migrating from python 2 to 3 https://blogs.dropbox.com/tech/2018/09/how-we-rolled-out-one...
Re:Pandas dropping Python 2 support
by pseudalopex on Thursday January 03, 2019 @09:28PM
(#18821486)
Facebook and Dropbox took years to switch. Instagram took at least 10 months. (I think that was just the big push.) They switched after the Python developers added compatibility features in 2011 and 2012 and libraries had time to catch up.
Here are all the milestones https://python3statement.org/